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ACRP ACRP-CP exam : ACRP Certified Professional Exam

ACRP-CP Exam Questions
  • Exam Code: ACRP-CP
  • Exam Name: ACRP Certified Professional Exam
  • Updated: Sep 28, 2026
  • Q & A: 127 Questions and Answers
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ACRP ACRP-CP Exam Syllabus Topics:

SectionWeightObjectives
Professionalism and Ethical Practice15%- Professional standards
  • 1. Role responsibilities and boundaries
  • 2. Confidentiality and conflict of interest
- Continuous improvement
  • 1. Professional development and education
  • 2. Quality assurance and process improvement
Study Design and Conduct17%- Study planning
  • 1. Study population and eligibility criteria
  • 2. Protocol development and amendments
  • 3. Sample size and statistical considerations
- Study implementation
  • 1. Site selection and activation
  • 2. Study monitoring and oversight
  • 3. Investigational product management
Regulatory and Compliance Requirements17%- ICH Guidelines
  • 1. E11 Pediatric Trials
  • 2. E9 Statistical Principles
  • 3. E8 General Considerations for Clinical Trials
  • 4. E6(R2)/E6(R3) Good Clinical Practice
  • 5. E2A Expedited Reporting
- Compliance procedures
  • 1. Audits and inspections
  • 2. Regulatory submissions and approvals
- International standards
  • 1. Declaration of Helsinki
Ethical and Participant Safety Considerations19%- Ethical principles
  • 1. Human subject protections and privacy
  • 2. Clinical equipoise and therapeutic misconception
- Clinical care and management of research participants
  • 1. Continuity of medical care
  • 2. Informed consent development and review
  • 3. Standard of care vs protocol requirements
- Safety monitoring and reporting
  • 1. Safety information evaluation and communication
  • 2. Adverse event identification and classification
Clinical Study Operations15%- Site management
  • 1. Site personnel training and delegation
  • 2. Study documentation and record keeping
- Project management
  • 1. Timeline and budget management
  • 2. Vendor and stakeholder management
Data Management and Informatics17%- Data collection
  • 1. Electronic data capture systems
  • 2. Case report form design and completion
- Data reporting
  • 1. Database lock and data transfer
  • 2. Data integrity and security
- Data quality control
  • 1. Query management and resolution
  • 2. Data validation and cleaning

ACRP Certified Professional Sample Questions:

Question #1

The PI should ensure that source data is:

  • A. On worksheets that are provided by the sponsor.
  • B. Accurately reflected in the eCRFs.
  • C. Kept on site for a minimum of 2 years.
  • D. Printed directly from the EMR.
Reveal Solution  Discussion  0

Correct Answer: B  🗳️

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Question #2

A PI is being considered for an industry-sponsored study. The PI sees approximately 20 patients per month who meet the study criteria. The PI does not have access to a Positron Emission Tomography (PET) scanner, which is required for the protocol. The PI is already taking part in three other studies. Should the Sponsor choose this PI?

  • A. No, the PI is taking part in too many ongoing studies to participate in this study.
  • B. No, the PI does not have the resources to perform all protocol-required procedures.
  • C. Yes, the PI can perform other imaging scans instead of the PET scans.
  • D. Yes, the PI has a sufficient patient population to take part in this study.
Reveal Solution  Discussion  0

Correct Answer: B  🗳️

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Question #3

All of the following are steps to assure an effective risk management approach while conducting a clinical study EXCEPT:

  • A. Controlling risk by setting thresholds of risk acceptability.
  • B. Assessing risk based on study impact.
  • C. Documenting all possible risk scenarios.
  • D. Identifying potential study risks.
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

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Question #4

The inclusion and exclusion criteria are in place so all subjects are:

  • A. Patients with the disease under study and will not have any adverse events.
  • B. Healthy and willing to complete the clinical trial.
  • C. Medically appropriate and protected from ethical vulnerability.
  • D. Ethically vulnerable and patients with the disease under study.
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

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Question #5

Confidentiality and privacy rules for protection of human subjects at research sites are determined by the:

  • A. Applicable regulatory authorities
  • B. Sponsor
  • C. PI
  • D. Applicable site SOPs
Reveal Solution  Discussion  0

Correct Answer: A  🗳️

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